Grace Boekhoff-Falk

Grace Boekhoff-Falk
Associate Professor

Ph.D., University of Wisconsin-Madison, 1991
Postdoctoral Research: University of Wisconsin-Madison 

Address: 264 Bardeen

Telephone: 608-262-1609

E-mail:

Department: Anatomy

Research Interests

Developmental Biology, Gene Expression, Hormones, Growth and Differentiation factors, and signal transduction

Research Fields

Developmental Genetics
Drosophila
Gene Expression 

Research Description:

My laboratory studies the development and evolution of limbs and neural structures. Our goals are to elucidate the developmental genetic programs underlying limb, auditory organ, olfactory organ and brain formation and to understand how they change during evolution to result in novel morphologies and functions.

Our efforts are focused on the genetic and biochemical interactions of the homeodomain transcription factors encoded by the Drosophila Distal-less (Dll), homothorax (hth), extradenticle (exd) and cut (ct) genes. We currently are using genetic, molecular (including gene expression array) and biochemical (including chromatin immunoprecipitation) approaches in the genetically tractable model organism, Drosophila melanogaster (fruitfly) to identify and investigate gene networks involved in limb and neural development. 

Representative Publications:

Search PubMed for more publications by Grace Boekhoff-Falk

Eberl, D.F. and G. Boekhoff-Falk. 2007. Development of the Drosophila Johnston´┐Żs organ. International Journal of Developmental Biology, 51:679-687. 

Ebacher, D.J.S., S.V. Todi, D.F. Eberl and G. Boekhoff-Falk. 2007. cut mutant Drosophila auditory organs differentiate abnormally and degenerate. Fly. 1:86-94. 

Zhao, G., Boekhoff-Falk, G., Wilson, B.A. and J. B. Skeath. 2007. Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS. PNAS 104:3847-3852. 

Zhao, G., Boekhoff-Falk, G., Wilson, B.A. and J. B. Skeath. 2007. Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS. PNAS 104:3847-3852. 

Zhao, G., Boekhoff-Falk, G., Wilson, B.A. and J. B. Skeath. 2007. Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS. PNAS 104:3847-3852.