John Doebley

John Doebley
Professor

Ph.D., University of Wisconsin-Madison, 1980
Postdoctoral Research: North Carolina State University 

Lab website: http://teosinte.wisc.edu/

Address: 5320 Genetics/Biotech

Telephone: 608-265-5803

E-mail:

Department: Genetics

Research Interests

My research focuses on the genetics of the evolution of plant form using maize as our model system and quantitative genetics as our main analytical approach.

Research Fields

Evolutionary & Population Genetics
Plants

Research Description:

Our group is trying to understand the genetic basis of the evolution of new morphological traits in plants. How many genes contribute to the evolution of a new trait? Are these genes regulatory or structural? Do the alterations in these genes affect protein function or gene expression? Research in my laboratory addresses these and related questions using maize and its wild relatives as a model system.

Representative Publications:

Search PubMed for more publications by John Doebley

Hung, H. Y., L. M. Shannon, F. Tian, P. J. Bradbury, C. Chen, S. A. Flint-Garcia, M. D. McMullen, D. Ware, E. S. Buckler, J. F. Doebley, J. B. Holland.  2012.  ZmCCT and the genetic basis of day-length adaptation underlying the post-domestication spread of maize.  Proc. Natl. Acad. Sci. USA 109: E1913-E1921.

Studer, A., Q. Zhao, J. Ross-Ibarra, and J. Doebley.  2011. A transposon insertion was the causative mutation in the maize domestication gene tb1. Nature Genetics 43: 1160-1163.

Zhao, Z., A. L. Weber, M. D. McMullen, K. Guill, and J. Doebley.  2011.  MADS-box genes of maize: frequent targets of selection during domestication.  Genetical Research 93: 65-75.

Weber, A. L., W. H. Briggs, J. Rucker, B. M. Baltazar, J. J. Sánchez-Gonzalez, P. Feng, E. S. Buckler and J. Doebley. 2008.  The genetic architecture of complex traits in teosinte (Zea mays ssp. parviglumis): new evidence from association mapping. Genetics 180:1221–1232.

Briggs, W. H., M. Mc Mullen, B. Gaut, and J. F. Doebley. 2007.  Linkage mapping of domestication loci in a large maize-teosinte backcross resource. Genetics 177:1915-28.

Clark, R, T. Nussbaum-Wagler, P. Quijada and J. Doebley. 2006.  A distant upstream enhancer at the maize domestication gene, tb1, has pleiotropic effects on plant and inflorescent architecture.  Nature Genetics 38: 594-597.

Wang, H., T. Nussbaum-Wagler, B. Li, Q. Zhao, Y. Vigouroux, M. Faller, K. Bomblies, L. Lukens, and J. Doebley.  2005.  The origin of the naked grains of maize.  Nature 436: 714-719.

Bomblies, K., R.-L. Wang, B. A. Ambrose, R. J. Schmidt, R. B. Meeley, and J. Doebley. 2003. Duplicate FLORICAULA/LEAFY homologs zfl1 and zfl2 control inflorescence architecture and flower patterning in maize. Development 130:2385-2395.

Vigouroux, Y., M. McMullen, C. T. Hittinger, K. Houchins, L. Schulz, S. Kresovich, Y. Matsuoka and J. Doebley. 2002. Identifying genes of agronomic importance in maize by screening microsatellites for evidence of selection during domestication. Proc. Natl. Acad. Sci. USA 99:9650-9655.

Matsuoka, Y., Y. Vigouroux, M. M. Goodman, J. Sanchez G., E. Buckler and J. Doebley. 2002. A single domestication for maize shown by multilocus microsatellite genotyping. Proc. Natl. Acad. Sci. USA 99:8060-8064.