University of Wisconsin–Madison
College of Agriculture and Life Sciences | School of Medicine and Public Health

Grace Boekhoff-Falk

Associate Professor

boekhofffalk@wisc.edu

608-262-1609

264 Bardeen

Education
Ph.D., University of Wisconsin-Madison (1991), Postdoctoral Research: University of Wisconsin-Madison
Department
Anatomy
Research Interests
Developmental Biology, Gene Expression, Hormones, Growth and Differentiation factors, and signal transduction
Research Fields
Developmental Genetics, Drosophila, Gene Expression

Research Description:
My laboratory studies the development and evolution of limbs and neural structures. Our goals are to elucidate the developmental genetic programs underlying limb, auditory organ, olfactory organ and brain formation and to understand how they change during evolution to result in novel morphologies and functions.

Our efforts are focused on the genetic and biochemical interactions of the homeodomain transcription factors encoded by the Drosophila Distal-less (Dll), homothorax (hth), extradenticle (exd) and cut (ct) genes. We currently are using genetic, molecular (including gene expression array) and biochemical (including chromatin immunoprecipitation) approaches in the genetically tractable model organism, Drosophila melanogaster (fruitfly) to identify and investigate gene networks involved in limb and neural development.


Representative Publications:
Search PubMed for more publications by Grace Boekhoff-Falk

Eberl, D.F. and G. Boekhoff-Falk. 2007. Development of the Drosophila Johnston’s organ. International Journal of Developmental Biology, 51:679-687.

Ebacher, D.J.S., S.V. Todi, D.F. Eberl and G. Boekhoff-Falk. 2007. cut mutant Drosophila auditory organs differentiate abnormally and degenerate. Fly. 1:86-94.

Zhao, G., Boekhoff-Falk, G., Wilson, B.A. and J. B. Skeath. 2007. Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS. PNAS 104:3847-3852.

Zhao, G., Boekhoff-Falk, G., Wilson, B.A. and J. B. Skeath. 2007. Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS. PNAS 104:3847-3852.

Zhao, G., Boekhoff-Falk, G., Wilson, B.A. and J. B. Skeath. 2007. Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS. PNAS 104:3847-3852.