Faculty studying disease biology
Reid Alisch
Psychiatry
The role of epigenetics in human health and disease processes, particularly in relation to the origins of mental illness.
Anjon Audhya
Biomolecular Chemistry
Regulation of vesicle biogenesis and membrane transport during development
Barak Blum
Cell and Regenerative Biology
Regenerative biology of the endocrine pancreas, genetics of type-1 and type-2 diabetes
David Brow
Biomolecular Chemistry
Molecular mechanisms of transcription termination and pre-mRNA splicing in yeast
Qiang Chang
Medical Genetics and Neurology
DNA methylation-dependent epigenetic regulation of brain functions
Lara Collier
Pharmacy
We use genetic and pharmacological approaches in mouse models to study disease etiology and treatment
Heidi Dvinge
Biomolecular Chemistry
Mechanisms of RNA splicing and splicing dysregulation in disease; downstream processing of RNA splice variants, including regulation of cellular localization and degradation; molecular function of protein isoforms of cancer-relevant genes
Feyza Engin
Biomolecular Chemistry
Diabetes and metabolic disorders, organelle dysfunction, stress responses, beta cell biology
Daniel S. Greenspan
Cell and Regenerative Biology
Genes important to vertebrate development and human disease
Anne Griep
Anatomy
My laboratory's focus is development and disorders of the visual system using the mouse as the model system
Aaron Hoskins
Biochemistry
RNA splicing, gene expression, fluorescence microscopy, RNA/protein complexes
Zhen Huang
Neurology and Nueroscience
Neuron and glial cell fate specification and differentiation, cortical neuron migration, migration disorders
Akihiro Ikeda
Medical Genetics
Identifying genes involved in aging, cell proliferation and neovascularization using mouse genetics
Nancy Keller
Bacteriology and Medical Microbiology and Immunology
Exploring genetic regulation of virulence and natural product synthesis by fungi
Judith Kimble
Biochemistry, Molecular Biology and Medical Genetics
Molecular regulation of germ line self-renewal and differentiation in C. elegans
Paul Marker
Pharmacy
Prostate biology, benign prostatic hyperplasia, and cancer using mouse genetics and clinical samples
Phil Newmark
Integrative Biology
Germ cell development and regeneration in planarians; developmental biology of parasitic flatworms
Nicole Perna
Genetics
Systems-scale evolutionary genomics of agriculturally, biomedically and industrially significant bacteria
David Schwartz
Chemistry and Genetics
Scalable discovery of human and cancer structural variation through invention and applications of single molecule systems
Paul Sondel
Pediatrics, Human Oncology and Medical Genetics
Antibody recognition of cancer cells in mice and in patients
Michael Taylor
School of Pharmacy, Pharmaceutical Sciences Division
Genetic dissection of blood-brain barrier development
Randal Tibbetts
Human Oncology
Genetic control of DNA replication and repair in mammals. Mechanisms of neurodegeneration in amyotrophic lateral sclerosis (ALS)
Beth A. Weaver
Cell and Regenerative Biology - McArdle Laboratory for Cancer Research
Mitosis, Aneuploidy, Cell Cycle, Cancer
Jill Wildonger
Biochemistry
How neuronal structure and function is shaped by the microtubule cytoskeleton and polarized transport
Jerry Yin
Genetics and Neurology
cAMP/PKA/dCREB2 signaling in sleep, memory formation, neurodegenerative diseases, developmental disabilities
Terri L. Young
Ophthalmology and Visual Sciences
Ophthalmic genetics, refractive error genetics, and pediatric ophthalmology clinical studies
Jing Zhang
Oncology
Using genetically engineered mouse models to study normal and mutant hematopoietic stem cell functions