Disease Biology

Reid Alisch

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Neurological Surgery
The role of epigenetics in human health and disease processes, particularly in relation to the origins of mental illness.

Alan Attie

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Biochemistry
Genetics of type 2 diabetes and related metabolic diseases

Anjon Audhya

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Biomolecular Chemistry
Regulation of vesicle biogenesis and membrane transport during development

Andrew Bent

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Plant Pathology
Molecular/Genetic Mechanisms of Plant Disease Resistance

Barak Blum

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Cell and Regenerative Biology
Regenerative biology of the endocrine pancreas, genetics of type-1 and type-2 diabetes

David Brow

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Biomolecular Chemistry
Molecular mechanisms of transcription termination and pre-mRNA splicing in yeast

Hao Chang

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Dermatology
Planar cell polarity in mammalian skin development and cancer

Qiang Chang

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Medical Genetics and Neurology
DNA methylation-dependent epigenetic regulation of brain functions

Lara Collier

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Pharmaceutical Sciences Division, School of Pharmacy
Genetic and pharmacological approaches in mouse models to study disease etiology and treatment

Kerri Coon

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Bacteriology
Insect-microbe interactions, impacts of gut microbes on the biology of disease vectors

Katie Drerup

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Integrative Biology
Neuronal Cell Biology, Neurodegenerative disease, Neurodevelopment

Feyza Engin

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Biomolecular Chemistry
Diabetes and metabolic disorders, organelle dysfunction, stress responses, beta cell biology

Daniel S. Greenspan

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Cell and Regenerative Biology
Genes important to vertebrate development and human disease

Melissa Harrison

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Biomolecular Chemistry
Transcriptional regulation during development

Aaron Hoskins

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Biochemistry
RNA splicing, gene expression, fluorescence microscopy, RNA/protein complexes

Zhen Huang

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Neurology and Nueroscience
Neuron and glial cell fate specification and differentiation, cortical neuron migration, migration disorders

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Biomolecular Chemistry and Medical Microbiology & Immunology
The goal of the Hull Laboratory is to understand how eukaryotic pathogen development and differentiation intersect with human disease. We take a hypothesis-driven experimental approach to discover the molecular mechanisms by which the model pathogenic fungus Cryptococcus reproduces and ultimately causes fatal meningitis. Students and post-docs in the lab are encouraged to work across disciplines to explore diverse aspects of biology to solve meaningful and challenging problems in biomedicine.

Anna Huttenlocher

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Pediatrics
Cell migration, Wound repair, Inflammation

Akihiro Ikeda

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Medical Genetics
Identifying genes involved in aging, cell proliferation and neovascularization using mouse genetics

Nancy Keller

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Medical Microbiology and Immunology
Fungal genetics, fungal/bacterial interactions, mining fungal genomes for bioactive chemicals

Judith Kimble

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Biochemistry, Molecular Biology and Medical Genetics
Molecular regulation of germ line self-renewal and differentiation in C. elegans

Peter Lewis

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Biomolecular Chemistry
Mechanisms of chromatin assembly, gene silencing, and epigenetic inheritance

Ci Ji Lim

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Biochemistry
Telomeres, chromatin structure-function relationship, protein-DNA interactions, molecular machines

Valentina Lo Sardo

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Cellular and Molecular Biology
Stem cell biology, reprogramming, cell fate determination, genetic risk factors for Cardiovascular disease and Cancer, genomics, transcriptomics, human specific genomic regions, evolution

Ahmed Mahmoud

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Cell and Regenerative Biology
Mammalian cardiac regeneration

Brian Parks

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Nutritional Sciences
Leveraging genetics to understand the pathways and molecular mechanisms that contribute to metabolic diseases.

Nicole Perna

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Genetics
Systems-scale evolutionary genomics of agriculturally, biomedically and industrially significant bacteria

Jason Peters

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Pharmaceutical Sciences
Gene networks and genetic tools in bacteria.

Vatsan Raman

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Biochemistry
High-throughput functional assays, variant effect prediction, human and microbial genomics

Steven Schrodi

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Medical Genetics
Human genomics of inflammatory diseases, statistical genetics, genetic architecture of diseases

David Schwartz

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Genetics and Chemistry
Discovery of fundamental molecular phenomena, which are harnessed within fully integrated systems for comprehensive genome analysis; creation of a cell-free system (“GenSyn”) for the direct fabrication of synthetic chromosomes, which adapt/advance micro- and nanofluidics technologies previously developed for genome analysis by the Schwartz group

Faculty studying disease biology