University of Wisconsin–Madison
College of Agricultural and Life Sciences | School of Medicine and Public Health

Disease Biology

Faculty studying disease biology

Caroline Alexander

Analysis of breast development, signaling and disease

Reid Alisch

The role of epigenetics in human health and disease processes, particularly in relation to the origins of mental illness.

Alan Attie

Genetics of type 2 diabetes and related metabolic diseases

Anjon Audhya

Biomolecular Chemistry
Regulation of vesicle biogenesis and membrane transport during development

Andrew Bent

Plant Pathology
Disease resistance and defense signal transduction in plants

Barak Blum

Cell and Regenerative Biology
Regenerative biology of the endocrine pancreas, genetics of type-1 and type-2 diabetes

David Brow

Biomolecular Chemistry
Molecular mechanisms of transcription termination and pre-mRNA splicing in yeast

Hao Chang

Planar cell polarity in mammalian skin development and cancer

Qiang Chang

Medical Genetics and Neurology
DNA methylation-dependent epigenetic regulation of brain functions

Lara Collier

We use genetic and pharmacological approaches in mouse models to study disease etiology and treatment

Heidi Dvinge

Biomolecular Chemistry
Mechanisms of RNA splicing and splicing dysregulation in disease; downstream processing of RNA splice variants, including regulation of cellular localization and degradation; molecular function of protein isoforms of cancer-relevant genes

Feyza Engin

Biomolecular Chemistry
Diabetes and metabolic disorders, organelle dysfunction, stress responses, beta cell biology

Michael Gould

Oncogenes and suppressor genes in mammary carcinogenesis

Daniel S. Greenspan

Cell and Regenerative Biology
Genes important to vertebrate development and human disease

Anne Griep

My laboratory's focus is development and disorders of the visual system using the mouse as the model system

Aaron Hoskins

RNA splicing, gene expression, fluorescence microscopy, RNA/protein complexes

Zhen Huang

Neurology and Nueroscience
Neuron and glial cell fate specification and differentiation, cortical neuron migration, migration disorders

Anna Huttenlocher

Cell migration, Wound repair, Inflammation

Akihiro Ikeda

Medical Genetics
Identifying genes involved in aging, cell proliferation and neovascularization using mouse genetics

Nancy Keller

Bacteriology and Medical Microbiology and Immunology
Exploring genetic regulation of virulence and natural product synthesis by fungi

Judith Kimble

Biochemistry, Molecular Biology and Medical Genetics
Molecular regulation of germ line self-renewal and differentiation in C. elegans

Peter Lewis

Biomolecular Chemistry
Epigenetic Mechanisms in Development and Cancer

Ahmed Mahmoud

Cell and Regenerative Biology
Mammalian cardiac regeneration

Paul Marker

Prostate biology, benign prostatic hyperplasia, and cancer using mouse genetics and clinical samples

David McCulley

Developmental biology and genetics related to lung and pulmonary vascular development and disease.

Phil Newmark

Integrative Biology
Germ cell development and regeneration in planarians; developmental biology of parasitic flatworms

Nicole Perna

Systems-scale evolutionary genomics of agriculturally, biomedically and industrially significant bacteria

David Schwartz

Chemistry and Genetics
Scalable discovery of human and cancer structural variation through invention and applications of single molecule systems

Paul Sondel

Pediatrics, Human Oncology and Medical Genetics
Antibody recognition of cancer cells in mice and in patients

Michael Taylor

School of Pharmacy, Pharmaceutical Sciences Division
Genetic dissection of blood-brain barrier development

Randal Tibbetts

Human Oncology
Genetic control of DNA replication and repair in mammals. Mechanisms of neurodegeneration in amyotrophic lateral sclerosis (ALS)

David Wassarman

Medical Genetics
Mechanisms underlying neurodegeneration

Beth A. Weaver

Cell and Regenerative Biology - McArdle Laboratory for Cancer Research
Mitosis, Aneuploidy, Cell Cycle, Cancer

Jill Wildonger

How neuronal structure and function is shaped by the microtubule cytoskeleton and polarized transport

Jerry Yin

Genetics and Neurology
cAMP/PKA/dCREB2 signaling in sleep, memory formation, neurodegenerative diseases, developmental disabilities

Terri L. Young

Ophthalmology and Visual Sciences
Ophthalmic genetics, refractive error genetics, and pediatric ophthalmology clinical studies

Jing Zhang

Using genetically engineered mouse models to study normal and mutant hematopoietic stem cell functions