Disease Biology

Faculty studying disease biology

Caroline Alexander

Address:
Oncology
Analysis of breast development, signaling and disease

Reid Alisch

Address:
Neurological Surgery
The role of epigenetics in human health and disease processes, particularly in relation to the origins of mental illness.

Alan Attie

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Biochemistry
Genetics of type 2 diabetes and related metabolic diseases

Anjon Audhya

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Biomolecular Chemistry
Regulation of vesicle biogenesis and membrane transport during development

Andrew Bent

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Plant Pathology
Disease resistance and defense signal transduction in plants

Barak Blum

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Cell and Regenerative Biology
Regenerative biology of the endocrine pancreas, genetics of type-1 and type-2 diabetes

David Brow

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Biomolecular Chemistry
Molecular mechanisms of transcription termination and pre-mRNA splicing in yeast

Hao Chang

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Dermatology
Planar cell polarity in mammalian skin development and cancer

Qiang Chang

Address:
Medical Genetics and Neurology
DNA methylation-dependent epigenetic regulation of brain functions

Lara Collier

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Pharmacy
We use genetic and pharmacological approaches in mouse models to study disease etiology and treatment

Feyza Engin

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Biomolecular Chemistry
Diabetes and metabolic disorders, organelle dysfunction, stress responses, beta cell biology

Michael Gould

Address:
Oncology
Oncogenes and suppressor genes in mammary carcinogenesis

Daniel S. Greenspan

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Cell and Regenerative Biology
Genes important to vertebrate development and human disease

Anne Griep

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Anatomy
My laboratory's focus is development and disorders of the visual system using the mouse as the model system

Aaron Hoskins

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Biochemistry
RNA splicing, gene expression, fluorescence microscopy, RNA/protein complexes

Zhen Huang

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Neurology and Nueroscience
Neuron and glial cell fate specification and differentiation, cortical neuron migration, migration disorders

Anna Huttenlocher

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Pediatrics
Cell migration, Wound repair, Inflammation

Akihiro Ikeda

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Medical Genetics
Identifying genes involved in aging, cell proliferation and neovascularization using mouse genetics

Nancy Keller

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Bacteriology and Medical Microbiology and Immunology
Exploring genetic regulation of virulence and natural product synthesis by fungi

Judith Kimble

Address:
Biochemistry, Molecular Biology and Medical Genetics
Molecular regulation of germ line self-renewal and differentiation in C. elegans

Peter Lewis

Address:
Biomolecular Chemistry
Epigenetic Mechanisms in Development and Cancer

Ahmed Mahmoud

Address:
Cell and Regenerative Biology
Mammalian cardiac regeneration

David McCulley

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Pediatrics
Developmental biology and genetics related to lung and pulmonary vascular development and disease.

Phil Newmark

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Integrative Biology
Germ cell development and regeneration in planarians; developmental biology of parasitic flatworms

Brian Parks

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Nutritional Sciences
Leveraging genetics to understand the pathways and molecular mechanisms that contribute to metabolic diseases.

Nicole Perna

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Genetics
Systems-scale evolutionary genomics of agriculturally, biomedically and industrially significant bacteria

Jason Peters

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Pharmaceutical Sciences
Gene networks and genetic tools in bacteria.

Steven Schrodi

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Medical Genetics
Human genomics of inflammatory diseases, statistical genetics, genetic architecture of diseases

David Schwartz

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Chemistry and Genetics
Scalable discovery of human and cancer structural variation through invention and applications of single molecule systems

Paul Sondel

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Pediatrics and Human Oncology
Antibody recognition of cancer cells in mice and in patients

Michael Taylor

Address:
School of Pharmacy, Pharmaceutical Sciences Division
Genetic dissection of blood-brain barrier development

Randal Tibbetts

Address:
Human Oncology
Genetic control of DNA replication and repair in mammals. Mechanisms of neurodegeneration in amyotrophic lateral sclerosis (ALS)

Han Wang

Address:
Integrative Biology
Genetic and Neural Dissection of Sleep in C. elegans

David Wassarman

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Medical Genetics
Mechanisms underlying neurodegeneration

Beth A. Weaver

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Cell and Regenerative Biology - McArdle Laboratory for Cancer Research
Mitosis, Aneuploidy, Cell Cycle, Cancer

Donna Werling

Address:
Genetics
Genetic risk for autism and other neuropsychiatric conditions, sex differences in neurobiology and risk for disease

Jill Wildonger

Address:
Biochemistry
How neuronal structure and function is shaped by the microtubule cytoskeleton and polarized transport

Jerry Yin

Address:
Genetics and Neurology
cAMP/PKA/dCREB2 signaling in sleep, memory formation, neurodegenerative diseases, developmental disabilities

Jing Zhang

Address:
Oncology
Using genetically engineered mouse models to study normal and mutant hematopoietic stem cell functions