Nancy Keller
Professor
Medical Microbiology and Immunology
Fungal genetics, fungal/bacterial interactions, mining fungal genomes for bioactive chemicals
Address
3476 Microbial Sciences Building
Website
https://sites.google.com/view/kellerlabuw/keller-lab-home
Education
Ph.D., Cornell University, Postdoctoral research with USDA
Department
Medical Microbiology and Immunology
Research Interests
fungal genetics, fungal/bacterial interactions, mining fungal genomes for bioactive chemicals
Research Fields
Disease Biology, Computational, Systems, and Synthetic Biology, Gene Expression, Genomics and Proteomics, Yeast and Other Fungi
Biography
Research Description:
fungal genetics, fungal/bacterial interactions, mining fungal genomes for bioactive chemicals
Representative Publications:
Search PubMed for more publications by Nancy Keller
Venkatesh N, Greco C, Drott MT, Koss MJ, Keller NM, Keller NP (2022) Bacterial hitchhikers derive benefits from fungal housing. Current Biol. Feb 24:S0960-9822(22)00239-1. doi: 10.1016/j.cub.2022.02.017.
Venkatesh N, Koss MJ, Greco C, Nickles G, Wiemann P, Keller NP (2021) Secreted secondary metabolites reduce bacterial wilt severity of tomato in bacterial-fungal co-infections. Microorganisms 9(10):2123. doi: 10.3390/microorganisms9102123. PMCID: PMC8537627
Wang W, Drott MT, Greco C, Luciano-Rosario D, Wang P, Keller NP (2021) Transcription Factor Repurposing Offers Insights into Evolution of Biosynthetic Gene Cluster Regulation. mBio. 12(4):e0139921. doi: 10.1128/mBio.01399-21.
Robey MT, Caesar LK, Drott MT, Keller NP, Kelleher NL (2021) An Interpreted Atlas of Biosynthetic Gene Clusters from 1000 Fungal Genomes. PNAS. 118(19):e2020230118. doi: 10.1073/pnas.2020230118.
Raffa N, Won TH, Sukowaty A, Candor K, Cui C, Halder S, Dai M, Landero Figueroa J, Schroeder FC, Keller NP (2021) Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper sufficiency and exhibit antimicrobial activity. PNAS. 118(8):e2015224118. PMCID: PMC7923669.
Niu M, Steffan BN, Fischer G, Venkatesh NT, Raffa NL, Wettstein M, Bok JW, Greco C, Zhao C, Berthier E, Oliw E, Beebe D, Bromley M, Keller NP (2020) Fungal oxylipins direct programmed developmental switches in filamentous fungi. Nature Communications. 11(1):5158. doi: 10.1038/s41467-020-18999-0.