Marisa Otegui
Position title: Associate Professor
Email: otegui@wisc.edu
Phone: 608-265-5703
Address:
Botany
Plant Molecular and Cell Biology; Plant Genetics and Development
- Address
- B119 Birge Hall
- Education
- PhD from University of La Plata Argentina; Postdoc on Plant Cell Biology at University of Colorado-Boulder
- Lab Website
- https://otegui.cellimaging.wisc.edu/
- Department
- Botany and Genetics
- Research Interests
- Plant Molecular and Cell Biology; Plant Genetics and Development
- Research Fields
- Cell Biology, Development, Gene Expression, Genomics and Proteomics, Plants
Research Description:
My research to date has focused on the mechanisms that regulate membrane and protein trafficking and degradation in plants and how they control plant development. My laboratory focuses on the mechanisms that regulate membrane and protein trafficking and degradation in plants and how they control plant development. I have combined genetic, molecular, biochemical, omics, and imaging approached to understand the degradation of cellular components through the endosomal pathway and autophagy. I devote part of my time and effort to optimize techniques for performing electron tomography and cryofixation of biological samples. This helps us to overcome some of the major current limitations in imaging endosomal trafficking and enable us to visualize directly protein coats on membranes, measure membrane curvature during vesicle formation, and perform structural characterization of membrane trafficking mutants. Through these efforts, we have identified new mechanisms of membrane budding in plant endosomes and novel autophagy receptors in different plant species.
Representative Publications:
Search PubMed for publications by Marisa Otegui